Analysis and Reflection on Typical Cases of Illegal and Irregular Online Pharmaceutical Sales

doi:10.2095-3593.2026.050017

Abstract

Abstract: Objective： To clarify the specific manifestations of illegal and irregular behaviors in online pharmaceutical sales in China， thereby providing references for drug regulatory authorities to conduct supervision and law enforcement in this field. Methods： Seven batches of typical cases of illegal and irregular online pharmaceutical sales published on the official website of the National Medical Products Administration from 2023 to 2024 were sorted out. The clue sources， types of illegal entities， case causes， administration panalties in these typical cases were analyzed. Results： Through case analysis， various manifestations and related characteristics of illegal and irregular behaviors in the field of online pharmaceutical sales were identified. Conclusion： Targeted thoughts and suggestions are put forward from multiple perspectives including laws and regulations， supervision mechanisms， platform responsibilities， and enterprise self-discipline， aiming to promote the standardized and healthy development of the online pharmaceutical sales and ensure the public′s medication safety.

Key words: font-size:medium, ">Online pharmaceutical sales； Typical cases； Supervision； Medication safety

CLC Number:

LIU Shan, ZHANG Dan, ZHANG Zhiyu, GONG Lei, LIU Xingping. Analysis and Reflection on Typical Cases of Illegal and Irregular Online Pharmaceutical Sales[J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 165-165-169.

References

[1] 米内网. 网上药店销售规模首超1000亿，药品销售额暴增40%[EB/OL]. (2020-0-26) [2025-11-02]. https： //3g. menet. com. cn/Article/Detial?aId=140035.
     [2] 米内网. 一文读懂|2024年零售终端药品销售规模达5740亿元，增速持续放缓[EB/OL]. (2025-02-17) [2025-11-02]. https： //3g. menet. com. cn/Article/Detial?aid=148607.
     [3] 米内网. 网上药店大涨超20%！40个畅销品牌出炉，国药集团、同仁堂……上榜 [EB/OL]. (2025-10-09) [2025-11-02]. https： //xueqiu. com/5923081507/355731943.
     [4] 施能进，石林勇，刘会佳. 药品网络销售质量风险防控及检查方法[J]. 黑龙江医药，2024，6（24）： 1316-1320.
     [5] 国家药品监督管理局．国家药监局公布5起药品网络销售违法违规典型案例（第四批）[EB/OL]. (2024-01-15) [2025-11-02]. https： //www. nmpa. gov. cn/yaowen/ypjgyw/ypyw/2024 0115172350140. html.
     [6] 国家药品监督管理局. 国家药监局公布5起药品网络销售违法违规典型案例（第五批）[EB/OL]. (2024-04-23) [2025-11-02]. https： //www. nmpa. gov. cn/yaowen/ypjgyw/ypyw/ 20240423085604182. html.
     [7] 国家药品监督管理局. 国家药监局公布4起药品网络销售违法违规典型案例（第六批）[EB/OL]. (2024-09-18) [2025-11-02]. https： //www. nmpa. gov. cn/ yaowen/ypjgyw/ypyw/20240918155149184. html.
     [8] 国家药品监督管理局. 国家药监局公布4起药品网络销售违法违规典型案例（第七批）[EB/OL]. (2024-12-23) [2025-11-02]. https： //www. nmpa. gov. cn/yaowen/ ypjgyw/ypyw/20241223155702158. html.
     [9] 黄炳生，吴生齐，张征. 我国药品网络销售现存风险及监管对策建议[J]. 中国药业，2022，31(10)：18-21.
     [10] 徐光辉，黄守勤，江灵芝. 药品网络销售监管问题与对策研究[J]. 卫生经济研究，2025，42（6）：32-39.
     [11] 吴少杰. 药品网络监管如何念好紧箍咒[N]. 健康报，2024-01-30（002）.
     [12] 徐维兴，药品网络销售风险及建议探析[J]. 中国药事，2025，39（5）：492-498.

[1]	WANG Lei, WANG Bing, JIN Sisi, SHEN Linghua. Observation on the Therapeutic Effect of Triptorelin on Abnormal Sexual Characteristics of Children with Precocious Puberty [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 216-216-221.
[2]	PANG Xiaochen, YANG Shasha, LI Yue, CHAI Zhongqiu, GAN Lu. Preparation and Preliminary Quality Evaluation of Chinese Medicine Transdermal Gel for Pediatric Mesenteric Lymphadenitis [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 237-237-243.
[3]	WEI Mingzhong, CHEN Chaoguang, LUO Qingmao, HUANG Shuting, JIANG Zhouqian, LIAO Aiqiu, LI Fan, YI Wenyan. Construction of Clinical Comprehensive Evaluation Index System of Antiretroviral Drugs for HIV Occupational Exposure Post-Exposure Prophylaxis#br# Based on Delphi Method and Analytic Hierarchy Process [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 231-231-236.
[4]	LIAO Hui, HE Chanjuan, YANG Hongxi, ZHANG Lu. Study on the Suitability of the Microbial Limit Test Method for Linglianhua Granules [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 189-189-195.
[5]	LI Hao, ZHANG Shuai, LIU Shifeng, SUN Caixia, QI Qiancheng. Research Progress on Analytical Methods for Nitrosamine Impurities in Pharmaceutical Products [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 170-170-176.
[6]	TANG Suqin, WANG Huisen, LIU Ming, ZHOU Qian. Prediction of Yin-nourishing Components in Rehmannia Radix and Multi-Components Thin-Layer Chromatography Identification [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 177-177-183.
[7]	LIN Yushuang, CHENG Lin, LIU Xiaoling, WU Yanyan, ZHU Zheng, GAO Danling, LIAO Yanping. Microbial Limit Test for Iodine-Containing Preparations by a Combined Neutralizer Method [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 196-196-200.
[8]	CHEN Chen, GONG Xuelian, HUANG Yan, SHEN Qingyun. Evaluation of the Anticoagulant Efficacy and Safety of Nafamostat Mesylate in Hemodialysis Patients [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 226-226-230.
[9]	XU Zhenya. Comparison of the Analgesic Effects of Butorphanol and Sufentanil Combined with Ketorolac Tromethamine for Postoperative PCIA after Total Hysterectomy [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 210-210-215.
[10]	RU Qingguo, LI Haiyan, LIU Yanan, JIANG Ludi, HUANG Xia, WANG Haibo. Research on the Determination Method and Risk Assessment of Aristolochic Acid Ⅰin Xinfang Biyan Capsules [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 184-184-188.
[11]	ZHANG Ping. Application Status of Finerenone in Resistant Hypertension [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 205-205-209.
[12]	CUN Shuhua, YANG Yanming, MA Xiaoling, CHEN Jiong, FAN Jincheng, WENG Zhiying. Data Mining and Analysis of Adverse Events of Luspatercept Based on FAERS and CAVRD [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 250-250-256.
[13]	HOU Jiachen, YANG Wenlong, FAN Minzhe, LI Linsen, WANG Yan, ZHU Dan. Preparation Process and Quality Standards of Jingbitong Mixture [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 244-244-249.
[14]	Ji Xue, ZHENG Jie, YAN Changyu, ZHU Dianlong, SUN Nan, LI Jun. Comparison of Alkaloid Content in Different Parts of Hyoscyamus niger L. [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 201-201-204.
[15]	ZOU Meng, LUO Caoyuan, LIANG Sijie, WU Wenjiang. Observation on the Application of Buzhong Yiqi Decoction in Wound Healing after Mixed Hemorrhoid Surgery [J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026, 43(3): 222-222-225.