CHINESE JOURNAL OF DRUG EVALUATION >

2025 , Vol. 42 >Issue 5: 351 - 351-355

DOI: https://doi.org/magtech-2025-07-11-00001

Research and Application Progress of Medical Magnesium-Based Implantable Devices

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  • 1.Yangtze River Delta Center for Medical Device Evaluation and Inspection of NMPA， Shanghai 201210， China；
    2.Center for Medical Device Evaluation， NMPA， Beijing 100076， China

Received date: 2025-07-11

  Revised date: 2025-08-26

  Accepted date: 2025-11-27

  Online published: 2025-12-15

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Abstract

Medical magnesium-based implant devices have emerged as a research hotspot in biodegradable implants due to their excellent mechanical properties， biodegradability， and biocompatibility. With rapid advancements in materials science and biomedical engineering in recent years， these devices have demonstrated significant advantages across clinical fields such as orthopedics and cardiovascular surgery， drawing widespread attention to both scientific achievements and commercialized products. This review systematically examines the corrosion characteristics and in vivo/in vitro degradation mechanisms of magnesium alloys， provides an in-depth analysis of their application scenarios in diverse medical domains， and focuses on clinical progress in fracture fixation， bone repair materials， cardiovascular stents， dental membranes， and biliary stents， highlighting representative domestic and international products. The findings aim to offer valuable references for researchers， medical device regulators， and industry stakeholders to accelerate the industrialization of magnesium-based implants.

Key words： ; font-size:medium; ">Magnesium； Biodegradable； Bone repair materials； Cardiovascular stents； Medical devices

Cite this article

YOU Mingyu, ZHANG Jiazhen, JIANG Shan, QU Chunge, TIAN Tian . Research and Application Progress of Medical Magnesium-Based Implantable Devices[J]. CHINESE JOURNAL OF DRUG EVALUATION, 2025 , 42(5) : 351 -351-355 . DOI: magtech-2025-07-11-00001

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