Investigation on Medication Adherence in Elderly Patients with Multiple Chronic Diseases and Its Related Factors

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  • 1.Nanyang Eighth People′s Hospital, Henan Nanyang 473000, China;
    2.The Third Affiliated Hospital of Henan University of Chinese Medicine, Henan Zhengzhou 450000, China

Received date: 2025-09-02

  Revised date: 2025-11-17

  Accepted date: 2026-04-01

  Online published: 2026-04-01

Abstract

Objective: To explore the current status and barriers of medication adherence in elderly patients with multiple chronic diseases. Methods: A survey on health and medication status was conducted in 511 elderly patients with multiple chronic diseases who treated in our hospitals from January 2024 to January 2025. The Elderly Chronic Disease Health Questionnaire, the Morisky Medication Adherence Scale, and the Chinese version of the Beliefs about Medication Specific Questionnaire were used for the investigation. Multivariate regression analysis was employed to identify the factors affecting medication adherence in elderly patients with chronic diseases. Results: The survey found that 188 patients (36.79%) had good medication adherence (all four items answered “no”), 323 patients (63.21%) had poor medication adherence (score 0-3). Among the 323 patients with poor adherence, those with a medication adherence score of 2 were the most common, totaling 143 patients, accounting for 44.27%. Of the 511 patients, 99 (19.37%) had a medication adherence score of 3, and only 17 patients (3.33%) had a medication adherence score of 0. Multivariate analysis showed that the sources of medical expenses, self-purchase of medicine over the past three months, and medication beliefs had statistically significant effects on medication adherence among elderly patients with chronic diseases (P<0.05). Conclusion: Particular attention should be paid to the impact of medical expense sources, self-purchase of medicine in the past three months, and medication beliefs on the medication adherence of elderly patients with chronic diseases.

Cite this article

CHENG Qianqian, ZHANG Yali . Investigation on Medication Adherence in Elderly Patients with Multiple Chronic Diseases and Its Related Factors[J]. CHINESE JOURNAL OF DRUG EVALUATION, 2026 , 43(1) : 77 -77-80 . DOI: 10.2095-3593.2026.030011

References

[1] 田纬,陶梦梦,李坤坤,等. 中国老年多重慢性病患者健康相关生命质量及其影响因素研究[J]. 中国全科医学, 2024, 27(11):1303-1309.
     [2] 姚钦元. 深圳某社区65岁及以上老年人常见慢性病患病情况及其影响因素分析[D]. 广州:广州医科大学,2023.
     [3] 赵钦风. 山东省老年多重慢性病患者的健康相关生命质量研究[D]. 济南:山东大学,2021.
     [4] 徐建明,罗松兴. 高血压患者用药依从性调查及影响因素分析[J]. 中国药物滥用防治杂志,2024,30(10):1823-1826.
     [5] 胡黎姿,王丹,熊浪宇,等. 中老年2型糖尿病患者用药依从性的Meta分析[J]. 中国现代医生,2024,62(18):62-68.
     [6] 卢甜甜,王洁,巫海娣,等. 中文版4条目Morisky用药依从性问卷在2型糖尿病患者中应用的信效度评价[C]//中华医学会糖尿病学分会教育管理研讨会暨国际糖尿病教育管理论坛,2014.
     [7] 冯薇. 药学服务对糖尿病患者血糖控制效果和用药依从性的影响[J]. 临床合理用药,2024,17(19):143-146.
     [8] 李晨,苏世菲. 老年2型糖尿病患者控糖方案及用药依从性调查分析[J]. 中国处方药,2024,22(5):153-155.
     [9] 朱呈娟. 临床药师干预对高血压患者血压控制效果及用药依从性的影响[J]. 临床合理用药,2024,17(26):156-159.
     [10] 李雅,王建,张红杰. 社区2型糖尿病老年患者用药依从性调查分析[J]. 中国药物滥用防治杂志,2024,30(2):252-254,263.
     [11] 孙梦瑶,邓敏,拓西平,等. 离退休居家老年患者用药依从性现状的现场调研及其影响因素分析[J]. 中国医院用药评价与分析,2024,24(4):498-501.
     [12] 罗莲英,陈美燕. 脊柱外科患者术后用药依从性监测与干预措施[J]. 黑龙江中医药,2024,53(4):153-155.
     [13] 付小丽,吴楠楠,胡洁萍,等. 维持性血液透析患者用药依从性的影响因素分析[J]. 现代养生,2024,24(11):805-808.
     [14] 李虹,刘伟,方园. 针对性沟通对PICC患者用药依从性、心理状态的影响[J]. 河北医药,2024,46(16):2512-2515.
     [15] 陈非,周丽群. 人文关怀对癌痛患者的疼痛控制及用药依从性的影响[J]. 西藏医药,2024,45(1):124-126.
     [16] 吉霞,高健,吉晨. 糖尿病肾病患者用药依从性影响因素研究及干预对策分析[J]. 中华保健医学杂志,2024,26(4):530-532.
     [17] 葛杨,朱雪清,何朝凯,等. 远程照护在PCI术后患者用药依从性管理中的研究进展[J]. 中国实用护理杂志,2024,40(27):2150-2155.
     [18] 郭和坚,朱亚兰,胡晓霞,等.基于2019版Beers标准评估门诊老年慢性病患者潜在不适当用药及影响因素[J]. 解放军药学学报, 2023, 36(2):154-158.
     [19] 徐建明,罗松兴. 2型糖尿病患者降糖药物使用情况及用药依从性调查分析[J]. 中国药物滥用防治杂志,2024,30(12):2215-2217.
     [20] 陈晓敏,张丽娜,李友佳.高龄老年2型糖尿病患者多重用药特点分析[J]. 中国全科医学,2023,26(10):1271-1277.
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