• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

• 药物研究 • 上一篇    下一篇

复方丹参滴丸治疗冠心病心绞痛的Meta分析

肖瑜,刘永军   

  1. 中国药科大学,中国药科大学
  • 收稿日期:2013-02-18 修回日期:2013-02-18 出版日期:2013-02-25 发布日期:2013-01-25

Meta-analysis of CSDP for Coronary Heart Disease Angina

Xiao Yu and LIU Yongjun   

  1. China Pharmaceutical University,China Pharmaceutical University
  • Received:2013-02-18 Revised:2013-02-18 Online:2013-02-25 Published:2013-01-25

摘要: 目的:以消心痛治疗作为对照组,评价复方丹参滴丸治疗冠心病心绞痛的临床疗效。方法:检索中国期刊全文数据库(2000-2012)和万方数据医药信息系统(2000-2012),按照循证医学的要求,对符合纳入标准的文献采用RevMan5.0专用软件进行Meta分析,选择心绞痛症状疗效、心电图改善效果作为效应指标。结果:对于心绞痛症状疗效的合并OR值为2.54(P<0.00001),95 %的CI为[1.89,3.42];心电图改善的合并OR值为2.42(P<0.00001),95 %的CI为[1.88,3.12],差异具有统计学意义,治疗组均优于对照组。结论:复方丹参滴丸较消心痛治疗冠心病心绞痛更有效,安全性较高。

Abstract: Objective:To evaluate the clinical efficacy of the CSDP in the treatment of coronary heart disease angina and use isosorbide dinitrate treatment as a control group. Method: Retrieve the China Academic Journal (2000-2012) and Wanfang Data of medical information systems ,according to the requirements of evidence-based medicine, Meta-analysis of the literature that met the inclusion criteria with the RevMan5.0 software, the effect of angina and the electrocardiogram improvement are selected as the effect indicators. Results: The for angina symptoms efficacy of combined OR value of 2.54(P<0.00001), 95% of CI[1.89,3.42]; the ECG improvement combined OR=2.42(P<0.00001),95% of CI[1.88,3.12], a statistically significant difference in the treatment group than the control group. Conclusion: CDSP treatment of angina pectoris is more effective and higher security than isosorbide dinitrate.