Abstract: Objective To identify pharmacoeconomic researches (PER) and survey of their epidemic characteristics in China.Method an electronic literature search of all ERs from inception to Dec 2012 was conducted using four Chinese databases. Two reviewers independently determined study eligibility and extracted related details. Excel and Meta Analyst 3.13 software were used to analyze related data.Result 488 studies were included, the frequency of PERs were found to increase during 1989-2012;Table showed the distribution of disease. 48.0% ERs were randomized control trials,52.0% used cost-effective analysis, 22.5% used cost-minimization analysis;10.7% used decision tree or Markov modes; 51.0% used the sensitivity; 25.6% used the discount rate;the composition of the cost generally included the prescription charge,cost of hospitalization, inspecting commission which are called direct cost, and 22.5% mentioned the indirect cost. Conclusion The number of PERs published in the journals was increasing annually. The future studies should pay more attentions to assess the design, discount rate, composition of the cost and quality of original studies.