Abstract: Objective： To evaluate the risk of anaphylactic response induced by ginkgo leaf extract/dipyridamole injection by animal experiment. Methods： In this study， every cavia cobaya and rat was given the preparations by intraperitoneal injection for sensitization. And 14 days later， excitation was performed to evaluate the risk of anaphylactic response. The excitation of every cavia cobaya was performed by intravenous injecting the same product to evaluate the risk of active systemic anaphylaxis (ASA) and the serum of every rat was collected to give nomal rats by intraperitoneal injection to assess the risk of passive cutaneous anaphylaxis (PCA). Results： In this study， No ASA was found in the cavia cobayas with the sensitization and excitation by the preparations（n=6）； also no PCA was found in the rats with the injection of the serum from other sensitized rats and excitation by the preparations（n=6）. Conclusion： With animal experiment， we concluded that ginkgo leaf extract/dipyridamole injection had a little probability of anaphylactic response.