我国传染病药物经济学研究方法学质量评价

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我国传染病药物经济学研究方法学质量评价

张素华,刘芳芳,姜红,卓玛拉措,赵丽婷,何耀,田金徽

兰州大学公共卫生学院兰州,兰州大学公共卫生学院兰州,兰州大学公共卫生学院兰州,兰州大学公共卫生学院兰州,兰州大学公共卫生学院兰州,兰州大学公共卫生学院兰州;兰州大学循证医学中心兰州,兰州大学循证医学中心兰州

收稿日期:2013-09-10 修回日期:2013-09-10 出版日期:2013-12-25 发布日期:2013-12-25
基金资助:
2011 年兰州大学中央高校基本科研业务费专项资金资助(编号：lzjbky2011-13)

Methodological Quality Assessment of Pharmacoeconomics Research of Infectious Diseases Published in Chinese

School of Public Health of Lanzhou University, Lanzhou 730000, China,,,,,,Evidence based medicine center of Lanzhou University

Received:2013-09-10 Revised:2013-09-10 Online:2013-12-25 Published:2013-12-25

摘要/Abstract

摘要： 目的：评价我国传染病药物经济学研究的方法学质量。方法：计算机检索四大中文文献数据库，全面收集我国传染病药物经济学研究，根据卫生经济学研究质量评价(QHES)量表单独进行报告质量评价，将评价结果录入Excel表格，利用Meta Analyst 3.13和RevMan 5.0软件对数据进行统计分析。结果：最终纳入44篇传染病药物经济学研究。从发表时间来看，2003年之后相关文献发表17篇，2004年之后发表27篇，近82%的研究由医院独立完成，22.7%的研究发表在CSCD收录的期刊上。纳入研究总得分为38～75（59.00?9.53）分，方法学质量评分为一般。分层分析显示，在发表时间和期刊级别方面的差异有统计学意义(P＜0.05)。结论：我国传染病药物经济学研究整体质量不高，突出表现在研究分析角度、亚组人群和资金资助等的报告上，建议将QHES量表加入杂志稿约，以提高药物经济学研究文章的质量。

Abstract: Objective： To assess the quality of economics research of infectious diseases in China.Methods： An electronic literature search of all related studies from inception to Dec 2012 was conducted using four Chinese database (CBM，CNKI，WANFANG，VIP). Using the following search terms “cost， cost effective， cost benefit， cost utility，infectious diseases” in the title and key words. Two reviewers independently assessed the quality by the Quality of Health Economic Studies (QHES) and extracted related details. The Meta Analyst 3.13 and RevMan 5.0 was used to analysis the related data.Results： 44 studies were identified and analyzed， 17 papers were published during 1991~2003， 27papers were published during 2004~2012. 82% studies were performed by doctor in hospital， 22.7% studies were published in CSCD database. The total score of included studies was 38~75（59.00±9.53）， the quality was moderate，the subgroup analysis showed that there were difference in publish time and level of journal (P＜0.05). Conclusion： The methodological quality of infectious diseases overall is low， especially in the study angle， the subgroup and funding， we recommend that editor could add the QHES checklists to the guide for authors.

张素华,刘芳芳,姜红,卓玛拉措,赵丽婷,何耀,田金徽. 我国传染病药物经济学研究方法学质量评价[J]. .