• 中国核心期刊(遴选)数据库收录期刊
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• 药物研究 • 上一篇    下一篇

雷替曲塞治疗结直肠癌的研究进展

黄荣华,马爱霞   

  1. 中国药科大学国际医药商学院,中国药科大学国际医药商学院
  • 收稿日期:2014-02-08 修回日期:2014-02-25 出版日期:2014-02-25 发布日期:2014-01-25

Research Progress of Raltitrexed Treatment of Colorectal Cancer

  1. School of International Pharmaceutical Business, China Pharmaceutical University,
  • Received:2014-02-08 Revised:2014-02-25 Online:2014-02-25 Published:2014-01-25

摘要: 目的:综述结直肠癌化疗药物的临床疗效及药物经济学评价结果。方法:基于结直肠癌的流行病学特征和治疗发展趋势,选取临床应用较多的以雷替曲塞或5- 氟尿嘧啶为主的化疗方案,并检索国内外相关文献,对其治疗结直肠癌的临床疗效和经济性进行综合分析。结果:各治疗方案表现出不同的临床疗效,而较少的药物经济学研究显示了雷替曲塞为主的化疗方案经济性。结论:雷替曲塞的临床疗效和经济性在总体上有优势,但还需更深入的研究。

Abstract: Objective: To summary of clinical efficacy and pharmacyoeconomic evaluation results of colorectal cancer chemotherapy. Methods: Based on the epidemiological characteristics and treatment trends of colorectal cancer, select the clinical application of raltitrexed or 5-fluorouracil-based chemotherapy, and retrieve relevant literature, then comprehensive analysis of its clinical efficacy and economy of colorectal cancer. Results: Each treatment programs exhibit different clinical efficacy, The fewer study showed pharmacoeconomics of raltitrexed-based chemotherapy. Conclusion: The research showed that clinical efficacy and economy of raltitrexed in general have an advantage, but needs further study.