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• 药品评价-循证医学研究 • 上一篇    下一篇

纳洛酮和单唾液酸四己糖神经节苷脂治疗颅脑损伤的间接Meta分析

徐丹妮,马骏捷,马爱霞   

  1. 中国药科大学国际医药商学院,中国药科大学国际医药商学院,中国药科大学国际医药商学院
  • 收稿日期:2014-04-14 修回日期:2014-05-28 出版日期:2014-06-25 发布日期:2014-06-25

Comparison Between Naloxone and Monosialoteterahexosyl Ganglioside in Treating Head Injury:An Indirect Meta-analysis

  1. China Pharmaceutical University,China Pharmaceutical University,
  • Received:2014-04-14 Revised:2014-05-28 Online:2014-06-25 Published:2014-06-25

摘要: 目的:系统评价纳洛酮和单唾液酸四己糖神经节苷脂(GM1)治疗颅脑损伤的疗效。方法:以间接Meta分析的方法对已有研究进行合并,系统评价两种药物治疗颅脑损伤的GOS恢复良好率。结果:纳洛酮和GM1的GOS恢复良好率分别为69.15%和55.61%。结论:在治疗颅脑损伤的GOS恢复良好率方面,纳洛酮明显优于GM1。

Abstract: Objective: To systematically evaluate the efficacy of curative effects of treating head injury between naloxone and GM1.Methods:GOS good recovery rate was taken as effectiveness indicator.An indirect Meta-analysis was developed.Results:The GOS good recovery rates are 69.15% and 55.61% for naloxone and GM1 respectively.Conclusion:The research showed that GOS good recovery rate in naloxone arm is better than that in GM1 arm.