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• 药物研究 • 上一篇    下一篇

地黄中梓醇含量与产区相关性研究

李民,辛杰,王春艳,张淹,张路   

  1. 山东东阿阿胶股份有限公司 国家胶类中药工程技术研究中心,山东东阿阿胶股份有限公司 国家胶类中药工程技术研究中心,山东东阿阿胶股份有限公司 国家胶类中药工程技术研究中心,山东东阿阿胶股份有限公司 国家胶类中药工程技术研究中心,
  • 收稿日期:2014-04-23 修回日期:2014-07-16 出版日期:2014-08-25 发布日期:2014-08-25

Study on the Correlation between the Content of Catalpol in Rehmannia and Producing Areas

李民,,王春艳, and 张路   

  1. Shan Dong Dong-E E-Jiao Co., Ltd.,,,
  • Received:2014-04-23 Revised:2014-07-16 Online:2014-08-25 Published:2014-08-25

摘要: 目的 对国内6个不同产区地黄梓醇含量进行相关性研究。方法 采用高效液相色谱法进行含量测定,采用TCMGIS一Ⅱ进行产地相似度分析。结果 各地地黄中梓醇的含量差别较大。含量最高的为河南武陟产地黄;其次为河南温县产区,河北安国产区,山东东阿阿胶GAP种植基地;辽宁地黄和山西襄汾产地黄含量均较低;与地黄道地产区生态相似度在90%以上区域主要集中在河南、山东和河北三省交界的平原区。结论 6个主要产区的地黄梓醇含量均符合国家药典规定,但产区间梓醇含量存在明显的差别;梓醇含量与其产区地理环境存在相关性。

Abstract: :Objective: To study and compare the content of Rehmannia from different prodution regions. Method:The contents were detected by the HPLC. Using TCMGIS-Ⅱ to analysis the similarity.Results:there was a big difference in the catalpol content. The highest content from the region of wuzhi,Henan;the following regions were wenxian,Henan,Anguo,Hebei Shandong Dong"e Ejiao GAP planting base . The productions from Liaoning and Xiangfen Shanxi have a low content of catalpol. The ecological similarity to the real estate area in more than 90% concentrated at the junction plain area in Henan, Shandong and Hebei provinces.Conclusion: The results indicated that the content of the six production regions all match the standard of the national ,but the difference between regions were significant. The similarity analysis of key ecological factors in different areas showed that the correlation between the content of Catalpol, and areas of geographical environment.