复方阿胶颗粒对缩宫素致大鼠痛经样反应的影响

复方阿胶颗粒对缩宫素致大鼠痛经样反应的影响

张路,王春艳,李民,赵婷婷,李士栋,张淹

国家胶类中药工程技术研究中心,国家胶类中药工程技术研究中心,国家胶类中药工程技术研究中心,国家胶类中药工程技术研究中心,国家胶类中药工程技术研究中心,国家胶类中药工程技术研究中心

收稿日期:2014-10-30 修回日期:2014-12-15 出版日期:2014-12-25 发布日期:2014-12-25
基金资助:
山东省科技发展计划——经典中药大品种阿胶技术升级（2013G0031901）

Effect of Fu Fang E Jiao Ke Li on Oxytocin Induced Dysmenorrhea-like Reaction

National Engineering Technology Research Center of Glue of Traditional Medicine,National Engineering Technology Research Center of Glue of Traditional Medicine,National Engineering Technology Research Center of Glue of Traditional Medicine,National Engine

Received:2014-10-30 Revised:2014-12-15 Online:2014-12-25 Published:2014-12-25

摘要/Abstract

摘要： 目的：通过复方阿胶颗粒对缩宫素致大鼠痛经样反应的影响，探讨复方阿胶颗粒缓解经期痛经症状的机制。方法：观察复方阿胶颗粒对缩宫素所致的体外子宫平滑肌剧烈收缩的影响，及其对痛经痉挛的抑制作用。结果：复方阿胶颗粒显著抑制缩宫素所致的体外子宫平滑肌的收缩，明显减少痛经大鼠扭体反应次数、延长发生扭体的潜伏期。结论：复方阿胶颗粒具有缓解经期痛经时痉挛及疼痛的作用。

Abstract: Objective： To explore the mechanism of fu fang e jiao ke li（FFEJ）relieve menstrual symptoms of dysmenorrheal by FFEJ on oxytocin induced dysmenorrhea-like reaction. Methods： To observe FFEJ on oxytocin induced uterine smooth muscle in vitro contraction of violent，and inhibition on spasmodic dysmenorrhea.Results：FFEJ could strongly inhibit the autonomic contraction activities of free ratuterus in those uterine smooth muscle in vitro induced by oxytocin.It also could significantly decrease the torsion times and prolong the incubation period writhing.Conclusion： FFEJ can relieve spasmodic dysmenorrheal and pain.

张路,王春艳,李民,赵婷婷,李士栋,张淹. 复方阿胶颗粒对缩宫素致大鼠痛经样反应的影响[J]. .