微小RNA在肝癌分子靶向治疗中的作用及研究进展

微小RNA在肝癌分子靶向治疗中的作用及研究进展

邓丹凤,裘云庆

浙江大学附属第一医院,浙江大学附属第一医院

收稿日期:2014-10-19 修回日期:2014-12-25 出版日期:2015-02-25 发布日期:2015-01-25
基金资助:
浙江省科技厅国际合作重大专项:“国家一类肝癌治疗药BZG-4000的作用机理和药效学研究”(2009C14030)

The Research Progress of MicoRNA in Molecular Targeting Treatment of Hepatocellular Carcinoma

邓丹凤 and 裘云庆

The FIrst Affiliated Hospital of Zhejiang University,

Received:2014-10-19 Revised:2014-12-25 Online:2015-02-25 Published:2015-01-25
Supported by:
International Cooperation Grant from Science Technology Department of Zhejiang Province:

摘要/Abstract

摘要： 微小RNA（miRNA）是一种长约18～25个碱基的非编码小RNA，它在肝癌的发生、发展、转移过程中发挥着重要的调控作用。近年来, 发现许多miRNA调节剂在多种肿瘤中发挥治疗作用，这提示着miRNA可能作为点一个新的靶点在肝癌的分子靶向治疗中发挥重要作用。本文就微小RNA在肝癌分子靶向治疗中作用的相关进展进行报道。

邓丹凤,裘云庆. 微小RNA在肝癌分子靶向治疗中的作用及研究进展[J]. .

邓丹凤 and 裘云庆. The Research Progress of MicoRNA in Molecular Targeting Treatment of Hepatocellular Carcinoma[J]. .

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