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王世家,陈永法
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摘要： 目的：评价碳酸钙、碳酸镧和盐酸司维拉姆三者在治疗高磷血症方面的经济性。方法：通过构建马尔可夫模型进行成本效果评价。结果：碳酸镧降磷效果最好，盐酸司维拉姆次之，碳酸钙最差，但考虑成本之后碳酸钙为最优方案。结论：在3倍人均GDP为支付阈值的条件下碳酸钙是最具有成本效果优势的方案。
Abstract: Objectives: To assess the cost-effectiveness of three kinds of phosphate binders as a treatment for hyperphosphatemia. Methods: A Markov model was developed to estimate outcome of QALYs, LYs and cost. Results: Compare to the calcium carbonate, Sevelamer hydrochloride was dominated, the ICER of the Lanthanum Carbonate is ￥160997, higher than the three times of GDP/QALY willingness to pay threshold. Conclusions: Calcium carbonate is the most cost-effectiveness strategy.
王世家,陈永法. 马尔可夫模型评价三种磷结合剂治疗高磷血症的研究[J]. .
陈永法. Markov model-based cost-effectiveness analysis of three phosphate binder[J]. .
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http://www.zgywpj.cn/CN/Y2015/V32/I3/162
