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• 药品评价-临床研究 • 上一篇    下一篇

CTX、替硝唑联合治疗ABP炎性指标的临床观察

许秋泳   

  1. 福建医科大学附属漳州市医院
  • 收稿日期:2015-12-16 修回日期:2016-02-03 出版日期:2016-02-25 发布日期:2016-01-25

Clinical Observation of Inflammatory Markers after Combined Treatment of Tinidazole and CTX in ABP

许秋泳   

  1. Zhangzhou Hospital Affiliated to Fujian Medical University
  • Received:2015-12-16 Revised:2016-02-03 Online:2016-02-25 Published:2016-01-25

摘要: [摘 要]目的:观察头孢噻肟钠(CTX)联合替硝唑对急性胆源性胰腺炎(Acute Biliacy Pancreatitis,ABP)炎性指标的作用。方法:将40例ABP患者随机分为两组:对照组,常规治疗 静脉滴注左氧氟沙星联合替硝唑;治疗组,常规治疗 静脉滴注CTX联合替硝唑。每组以7天为一个疗程。治疗前后对各组患者进行白细胞计数、血、尿淀粉酶等指标以及腹部CT和腹疼症状检查。结果:两组对ABP均有明显的治疗作用(P<0.05)。CTX联合替硝唑治疗组治疗效果明显优于左氧氟沙星联合替硝唑治疗组(P<0.05)。结论:CTX联合替硝唑可应用于临床治疗ABP。

Abstract: [Abstract]Objective:To observe the situation of inflammatory markers after combined treatment of cefotaxime sodium(CTX) and tinidazole in patients with acute biliacy pancreatitis(ABP). Methods:40 patients with ABP were randomly divided into two groups:patients were treated with levofloxacin and tinidazole intravenously on the basis of a conventional therapy as control group; patients were treated with CTX and tinidazole intravenously on the basis of a conventional therapy as treatment group. One type of treatment requires 7 days in both groups. After that, leucocyte count, blood and uric amylases were detected, then CT and pain level in abdomen were estimated. Results:Both groups have good therapeutic effects on ABP (P<0.05). Moreover, combination treatment of CTX and tinidazole is superior to that of levofloxacin and tinidazole (P<0.05). Conclusion:Combination treatment of CTX and tinidazole may be an effective method to treat ABP in clinic.