Abstract: We conclude that Qiwei Jianghuang liniment has certain therapeutic effects for acne and seborrhea by systematic review and analysis of the pharmacological research and clinical study on the efficacy and safety. It also have therapeutic effects on allergic skin disease, tinea corporis,tinea cruris,tinea pedis and alopecia areata.The post-marketing clinical studies also showed that it causes several adverse reactions, such as local pain and local irritation. Whereas, the design of current clinical study and the drug risk evaluation are insufficient. We propose that it is an appropriate way to provide further scientific proof and ensure rational efficacy drug use by conducting well-designed and good quality post-marketing clinical study on reevaluation the safety and efficacy according to the character of the product，the risk of interactions with other medications.