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胺碘酮治疗老年心律失常疗效与安全性分析

陈光   

  1. 济南市血液供保中心
  • 收稿日期:2017-06-12 修回日期:2017-07-03 出版日期:2017-10-25 发布日期:2017-10-25

An Analysis on Effect and Safety of Samiodarone in the Treatment of Arrhythmia in the Aged

  1. Ji'nan blood supply and Protection Center
  • Received:2017-06-12 Revised:2017-07-03 Online:2017-10-25 Published:2017-10-25

摘要: 目的 对胺碘酮治疗老年心律失常的临床疗效与安全性进行探究。方法 于我院2014年5月-2016年5月期间住院治疗的心律失常的老年患者中选取90例为研究对象,依照患者住院号奇偶数分为对照组(45例)和观察组(45例),对照组患者接受临床常规综合治疗,在对照组基础上观察组加以口服胺碘酮治疗,分析临床疗效、不良反应情况.。结果 治疗后,观察组患者心律失常总有效率明显高于对照组,差异均具有统计学意义(p<0.05);观察组心功能改善总有效率明显高于对照组,差异具有统计学意义(p<0.05);观察组心律次数、QT间期延长等指标均较对照组优,差异具有统计学意义(p<0.05);同时观察组不良反应率低于对照组,差异具有统计学意义(p<0.05)。结论 心律失常老年患在接受常规综合治疗的基础上加以服用胺碘酮治疗,临临床疗效显著,其安全性、有效性均较高。

Abstract: Objective: To explore the clinical effect and safety of amiodarone in the treatment of arrhythmia in the aged. Methods: 90 elderly patients with arrhythmia treated in this hospital from May 2014 to May 2016 were selected as the research objects and they were divided into the control group (45 cases) and observation group (45 cases) according to the odd and even hospital numbers. Patients in the control group were given the clinical routine comprehensive treatment, while patients in the observation group were given the oral administration of amiodarone based on the routine treatment. The clinical effect and adverse reactions were analyzed. Results: After the treatment, the overall response rate of arrhythmia for patients in the observation group was significantly higher than that in the control group, with the statistical difference (p<0.05); the overall response rate of cardiac function for patients in the observation group was significantly higher than that in the control group, with the statistical difference (p<0.05); the indicators of heart rate and QT interval prolongation for patients in the observation group were significantly better than that in the control group, with the statistical difference (p<0.05); and the rate of adverse reactions for patients in the observation group was lower than that in the control group, with the statistical difference (p<0.05). Conclusion: The oral administration of amiodarone for the elderly patients with arrhythmia based on the routine treatment has the obvious clinical effect with the high safety and effectiveness.