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双黄连口服液(儿童型)联合干扰素α1b 治疗小儿手足口病的临床观察

徐泽合   

  1. 河南中医药大学第一附属医院儿科
  • 收稿日期:2018-03-21 修回日期:2018-06-14 出版日期:2018-08-25 发布日期:2018-08-25

Clinical Observation on Hand-mouth-foot Disease in Children with Shuanghuanglian Oral Liquid (Only for Children) Combined with Interferon α1b

Xuzehe   

  1. 河南中医药大学第一附属医院儿科
  • Received:2018-03-21 Revised:2018-06-14 Online:2018-08-25 Published:2018-08-25

摘要: 目的:观察双黄连口服液(儿童型)联合干扰素治疗小儿手足口病的临床疗效。方法:将患儿随机分为对照组和观察组各32例,对照组给予干扰素肌内注射,治疗组给予干扰素肌内注射联合口服双黄连口服液(儿童型)治疗,观察其临床疗效。结果:治疗组治疗总有效率为96.88%,与对照组总有效率71.88%相比,差异有统计学意义(P<0.05);治疗组患儿发热、手足疱疹、口腔黏膜疱疹等临床症状消失时间明显优于对照组(P<0.05)。结论:双黄连口服液(儿童型)联合干扰素治疗小儿手足口病能够明显缩短临床表征时间,临床治愈效果较好,可为临床用药提供参考。

Abstract: Objective: To study the effects of the Shuanghuanglian oral liquid(only for children) combined with interferon in the treatment of hand-mouth-foot disease in children. Methods: Children were randomly divided into control group (n=32) and treatment group (n=32). The control group were treated with interferon intramuscular injection and the treatment group received interferon intramuscular injection combined with Shuanghuanglian oral liquid (only for children). Results: The total effective rate of the treatment group was 96.88%, compared with the total effective rate of 71.88% in the control group, there was significant difference (P<0.05), and the time of disappearance of clinical symptoms such as oral mucosal herpes, herpes of hand and foot, fever in the treatment group was significantly shorter than that in the control group (P<0.05).Conclusion: Shuanghuanglian oral liquid (only for children) combined with interferon can significantly shorten the time of clinical manifestation and improve the clinical cure rate. It is worth popularizing and applying in clinic.