Abstract: Objective： Cases of ADR/ADE reports of our hospital were collected，to analyze the characteristics， causes of the cases and the preventive measures of the adverse drug reaction/event(ADR/ADE)，and in order to provide scientific basis for clinical rational use of drugs. Methods： 102 cases of ADR/ADE collected by our hospital were analyzed statistically and retrospectively. Results：Among 102 cases of ADR/ADE reports， there were more females than males(58/44)， the number of patients aged ＞60 years old took the lead(31.37%). There were 6 new and serious ADR/ADE cases(5.88%). The most common ADR/ADE were induced by intravenous infusion(50. 00%). A total of 8 kinds of drugs were involved， including 62 categories， among which anti-infective drugs dominated the first place(35.29%). ADR/ADE mainly involved digestive system damage(33.60%)， skin and its accessories damage (21.60%). The were 40 cases of irrational use of medication(39.22%). Conclusion： The factors which lead to the ADR/ADE include irrational use of medication， patients， drugs and inappropriate usage. We should enhance the monitoring of ADR/ADE， promote the rational drug use in clinic， so as to improve the security and effectiveness of clinical medication.