单个病例数据Meta分析研究现状

单个病例数据Meta分析研究现状

田金徽,杨克虎,Fujian Song,张俊华

兰州大学循证医学中心,兰州大学循证医学中心,英国东英格利亚大学医学院,英国诺威奇 NR TJ;英国东英格利亚大学医学院,英国诺威奇 NR TJ,

收稿日期:2019-07-25 修回日期:2019-07-25 出版日期:2019-08-28 发布日期:2019-08-28
基金资助:
甘肃省循证医学与临床转化重点实验室开放基金(项目编号：20170203；项目名称：循证医学方法学研究)

The Descriptive Analysis of the Individual Patient Data Meta Analysis

Tian Jinhui,, and

Gansu Health Vocational College,,,

Received:2019-07-25 Revised:2019-07-25 Online:2019-08-28 Published:2019-08-28

摘要/Abstract

摘要： 目的：全面收集并分析单个病例数据Meta分析（individual patient data meta analysis，IPDMA)，为我国学者IPDMA的撰写提供参考。方法：检索主要英文数据库获取IPDMA，纳入以英文全文形式发表、研究对象为来自随机对照试验的患者、关注干预措施的有效性和安全性的IPDMA。用Excel软件建立数据提取表，提取数据并进行分析整理。结果：检索获取558篇IPDMA，发文数量总体呈上升趋势；558篇IPDMA发表在211种期刊上，被SCI收录的期刊205种，占期刊总数的97.16％，刊载的IPDMA数量为92.65％；42.65%的IPDMA来自英国和美国；研究前5位疾病分别是缺血性脑卒中、急性心肌梗死、抑郁、肺癌和乳腺癌。结论：英国和美国在IPDMA研究领域占据主导地位，我国在IPDMA研究中具有很大的潜力。

Abstract: Objective： To collect and analyze comprehensive individual patient data meta analysis (IPDMA)， provide a reference for our future IPDMA writing and submission. Methods： We searched four English database access to English IPDMA， and which included the patients came from the randomized controlled trials， focused on the efficiency and safety of interventions， and published by full text. The data extraction sheet was established by Excel software， data extraction and analysis finishing. Results： 558 IPDMA were included， the number of IPDMA was rising from 1991 to 2018. 558 IPDMA distributed on 212 journals， 105 kinds of journals indexed by SCI， accounting for 97.16% of the total journals， which published the number of IPDMA was 92.65%. The UK and the USA published the number of IPDMA was 42.65%. The top five diseases were ischemic stroke， acute myocardial infarction， depression， lung cancer and breast cancer. Conclusion： Most of IPDMA was came from the UK and the USA， China has great potential in the field of IPDMA.

田金徽,杨克虎,Fujian Song,张俊华. 单个病例数据Meta分析研究现状[J]. .

Tian Jinhui,, and. The Descriptive Analysis of the Individual Patient Data Meta Analysis[J]. .

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