关键词: 僵蚕, 白僵菌素, 草酸铵, 质量评价

Abstract: Objective： In response to the quality variations observed in Bombyx Batryticatus， an assessment of Bombyx Batryticatus from different origins was conducted， leading to improve the quality standard. Methods： HPLC methods were established to determine the content of beauvericin and ammonium oxalate in Bombyx Batryticatus. 58 batches of representative medicinal materials and decoction pieces of Bombyx Batryticatus from different sources were analyzed. Results： Among the 58 batches of samples， beauvericin and ammonium oxalate were not detected in 10 batches， accounting for 17.2%. The contents of beauvericin ranged from 0.010 1% to 0.119 2%， and the contents of ammonium oxalate ranged from 4.71% to 10.84%， showing a significant positive correlatation (P<0.01). Conclusion： The established methods have strong specificity， high sensitivity and good repeatability， which can effectively evaluate and control the quality of Bombyx Batryticatus. There is a high quality risk of Bombyx Batryticatus， and the quality standard needs to be further improved.

Key words: Bombyx Batryticatus, Beauvericin, Ammonium oxalate, Quality evaluation