• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

• 药品评价-循证医学研究 • 上一篇    下一篇

依立雄胺治疗良性前列腺增生症有效性、安全性研究综述

周清,马爱霞   

  1. 中国药科大学国际医药商学院,中国药科大学国际医药商学院
  • 收稿日期:2014-02-13 修回日期:2014-03-01 出版日期:2014-06-25 发布日期:2014-06-25

The Review of Efficacy and Safety of Epristeride in the Treatment of Benign Prostatic Hyperplasia

  1. International Pharmaceutical Business School,China Pharmaceutical University,Jiangsu Nanjing 211198,
  • Received:2014-02-13 Revised:2014-03-01 Online:2014-06-25 Published:2014-06-25

摘要: 依立雄胺是一种非竞争性2型5-α还原酶抑制剂,在治疗良性前列腺增生症(BPH)方面有显著疗效,能显著缩小前列腺体积,增加最大尿流率,减少残余尿量,且无严重不良反应。现拟对依立雄胺治疗良性前列腺增生症的有效性及安全性作一综述,以期为BPH临床治疗方案的选择提供理论和实践依据。

Abstract: Epristeride is a non-competitive inhibitors of type 2 5-α reductase which has a significant effect in the treatment of benign prostatic hyperplasia(BPH). It can significantly reduce prostate volume, increase maximum urinary flow rate and reduce residual urine volume, and has no serious adverse reactions. This article would have briefly reviewed the efficacy and safety of epristeride for treating benign prostatic hyperplasia.