Abstract: Objective： To observe the clinical effects of budesonide， azithromycin injection combined with terbutaline sulphate solution for nebulization in the treatment of pediatric acute bronchitis. Methods： 100 patients with infantile acute bronchitis were divided into control group and observation group by random number table method.All pediatric acute bronchitis were given electrolyte supplement， cough and asthma， spasmolysis， nutritional support and other conventional treatment. Based on it.The control group was given azithromycin injection 10 mg?kg-1， dissolved into the glucose injection 250 mL， intravenous infusion of 1 h， once a day. Take 2 mg terbutaline sulphate solution of nebulization， dissolve into the sodium chloride injection 2 mL， atomization inhalation， every time 15 min， twice a day. Observation group was additionally given 1 mg inhalation of budesonide aerosol，10 min each time， 3 times a day.Two groups were treated for 10 d. Results： Children of observation group the cough disappeared time， temperature recovery time，vomit disappearance time， and the disappearance of lung dry and wet rales and shortening of the hospitalization time， had a statistically significant difference respectively (P<0.05). The effective rate of the observation group (96.00%) was better than that of the control group (84.00%)， and there were differences (P<0.05). Conclusion： The clinical effects of budesonide， azithromycin injection combined with terbutaline in the treatment of pediatric acute bronchitis were remarkable， and it was worth further promotion.