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• 药物研究 • 上一篇    下一篇

化积口服液促小鼠胃肠动力作用研究

刘卫德,刘宁   

  1. 江西省药品检验检测研究院,江西省药品检验检测研究院
  • 收稿日期:2017-08-11 修回日期:2017-08-11 出版日期:2017-12-25 发布日期:2017-12-25
  • 基金资助:
    江西省科技社会发展项目(20151BBG70041) 刘宁 王琪*

Study of the effect of Huaji oral liquid on the gastrointestinal motility

Liu Weide and   

  1. Jiangxi Institute for Drug Control,Jiangxi Province Engineering Research Center of Drug and Medical Device Quality. Nanchang 330029,Jiangxi Institute for Drug Control,Jiangxi Province Engineering Research Center of Drug and Medical Device Quality. Nanchan
  • Received:2017-08-11 Revised:2017-08-11 Online:2017-12-25 Published:2017-12-25

摘要: 目的:研究化积口服液治疗小儿厌食、疳积等疾病的作用机理。结果:本研究通过小鼠小肠推进功能试验及胃排空试验,对化积口服液促进小鼠胃肠动力作用进行了初步研究。结果:与模型组比较,化积口服液能促进硫酸阿托品负荷小鼠小肠推进功能(P<0.05);与空白对照组比较,化积口服液能促进小鼠胃排空(P<0.05)。结论:化积口服液具有增强小鼠小肠推进功能,促进胃排空的作用。

Abstract: Objective: In order to reveal its mechanism of Huaji oral liquid for treatment of infantile anorexia, malnutrition and other diseases. Methods: We researched the effect of Huaji oral liquid in promoting gastrointestinal motility through the test of mouse intestinal propulsion and gastric emptying. Results: Compared with the model group, Huaji oral liquid can increase the intestinal propulsive function of mice injected with atropine sulfate(P<0.05). And compared with the normal group, Huaji oral liquid help to enhance the gastric emptying(P<0.05). Conclusion: We confirmed the effect of Huaji oral liquid in increase mice intestinal propulsive function and gastric emptying.