GC法同时测定香砂养胃片中去氢木香内酯、厚朴酚、和厚朴酚的含量

GC法同时测定香砂养胃片中去氢木香内酯、厚朴酚、和厚朴酚的含量

赵磊,郭彩芳,高楠楠,孙艳涛

四平市食品药品检验所,四平市中小企业创新发展服务中心,四平市食品药品检验所,吉林师范大学化学学院

收稿日期:2018-06-14 修回日期:2018-09-11 出版日期:2018-10-25 发布日期:2018-10-25

Determination of Dehydrocostuslactone Homokiol and Magnololin Xiangsha yangwei Tablet by GC

ZHAO Lei,, and

Siping City Institute for Food and Drug Control,Jilin Siping,The service center for innovation and development of minor enterprises in Siping City,Jilin Siping,Siping City Institute for Food and Drug Control,Jilin Siping,Jilin Normal University College

Received:2018-06-14 Revised:2018-09-11 Online:2018-10-25 Published:2018-10-25

摘要/Abstract

摘要： 目的：建立气相色谱（GC）法测定香砂养胃片中去氢木香内酯、厚朴酚与和厚朴酚的含量。方法：采用色谱柱为WondaCAP5 30 m×320 μm×0.25 μm毛细管色谱柱；检测器：FID检测器。进样口温度：250 ℃；柱温箱温度：210 ℃；检测器温度：280 ℃；载气流速：3.0 mL·min-1；进样量：1 μL。结果：去氢木香内酯在1.996~199.6μg·mL-1；厚朴酚在5.123~512.3 μg·mL-1；和厚朴酚在2.609~260.9μg·mL-1的范围内，线性关系良好（r＞0.999 1）平均回收率分别为97.3%（RSD=1.1%）、98.6%（RSD=1.2%）和97.4%（RSD=1.9%）结论：建立方法简单、准确、重现性好，可用于控制香砂养胃片中3种活性成分的含量。

Abstract: Objective：To establish GC method for determination of Dehydrocostuslactone Homokiol and Magnolol in Xiangsha Yangwei Tablet. Methods： GC was used by WondaCAP5 30 m×320 μm×0.25 μm Capillary column. The detector was FID Inlet temperature was 250 ℃； column temperature was 210 ℃ and the detector temperature was 280 ℃. The flow rate was 3 mL·min-1. Results： The linear equations of Dehydrocostuslactone Homokiol and Magnolol were in good linear range (r＞0.999 1). The average recovery of Dehydrocostuslactone Homokiol and Magnolol was 97.3%（RSD=1.1%）、98.6%（RSD=1.2%） and 97.4%（RSD=1.9%）. Conclusion： The method is simple， accurate and reproducible，and it can be used to control the quality of Xiangsha Yangwei Tablet.

赵磊,郭彩芳,高楠楠,孙艳涛. GC法同时测定香砂养胃片中去氢木香内酯、厚朴酚、和厚朴酚的含量[J]. .

ZHAO Lei,, and. Determination of Dehydrocostuslactone Homokiol and Magnololin Xiangsha yangwei Tablet by GC[J]. .

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