Abstract: Objective: Using inductively coupled plasma mass spectrometry to analyze the detection of metallic elements in foeniculi fructus, and to identify the anti－tumor effects of the metal elements in foeniculi fructus, initially to explore the anti－tumor mechanism of foeniculi fructus for its rational use. Methods: By microwave digestion and inductively coupled plasma mass spectrometry, using semi－quantitative and quantitative analysis model, to carry out the metal element in foeniculi fructus qualitative and quantitative analysis of the research to identify the elements associated with anti-tumor mechanisms, preliminary inquiry foeniculi fructus′ antitumor mechanism. Results: The results showed that foeniculi fructus contains a higher content of Na, Mg, Ca, Fe, Zn, Mn, Ba metal elements initially identified through literature research, foeniculi fructus' anti-tumor mechanism of Na, Mg, Ca，Fe, Zn, Mn and other metals. Conclusion: The group from the metal point of view to lay the foundation for carrying out the mechanism of the anti-tumor effects of foeniculi fructus.