左氧氟沙星不良反应/不良事件防范性研究

• 药品评价-安全性研究 • 下一篇

左氧氟沙星不良反应/不良事件防范性研究

汪龙,程军

安徽省蚌埠市第三人民医院药学部,蚌埠市第三人民医院

收稿日期:2014-12-05 修回日期:2015-04-08 出版日期:2015-04-25 发布日期:2015-04-25
基金资助:
蚌埠市医疗卫生科技计划项目

A Study of Prevention of Adverse Drug React/Adverse Drug Event of LevofloxacinCHENG Jun,zhang Shi-yong(Department of Pharmacy,The Third People’s Hospital Bengbu,Bengbu Anhui 233000,China)

汪龙 and 程军

The Third People’s Hospital Bengbu,

Received:2014-12-05 Revised:2015-04-08 Online:2015-04-25 Published:2015-04-25

摘要/Abstract

摘要： 目的：了解我院左氧氟沙星不良反应/不良事件(Adverse Drug React/Adverse Drug Event,ADR/ADE)报表情况,分析可防范性ADR/ADE,促进临床合理用药。方法：对我院2009～2013年上报的左氧氟沙星致ADR/ADE报表进行回顾性调查,参考相关资料进行可防范性分析。结果：128例ADR／ADE报表中,可防范性ADR/ADE为52例(40.6%),其中48例适应证不合理,2例配伍禁忌,1例有药物相互作用,5例超剂量。结论：临床应重视合理使用左氧氟沙星,减少可防范性ADR/ADE发生。

Abstract: Objective Objective：To assess preventability of adverse drug react/adverse drug events(ADR/ADE) of Levofloxacin Through ADR/ADE reports and To promote rational drug use. Methods ADR/ADE induced by Levofloxacin collected in our hospital from 2009～2013 were analyzed according to the related guidelines and documents. Results In the total 128cases,the rate of preventable ADR/ADE were 40. 6%.The complicated outcomes showed 48 patients with no existing reasonable drug application with the indication,2 patients with incompatibility of drug, 1patients with drug interaction,5 patient with of overdose. Conclusion Levofloxacin should be applicated strictly according to indication and proper dosage; with special attention for prohibitive compatibility in order to promote clinical curative efficacy and reduce adverse react/ adverse drug event.

汪龙,程军. 左氧氟沙星不良反应/不良事件防范性研究[J]. .

汪龙 and 程军. A Study of Prevention of Adverse Drug React/Adverse Drug Event of LevofloxacinCHENG Jun,zhang Shi-yong(Department of Pharmacy,The Third People’s Hospital Bengbu,Bengbu Anhui 233000,China)[J]. .

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