• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

• 药品评价-安全性研究 • 上一篇    下一篇

44例转化糖注射剂不良反应/事件分析

谢晓燕   

  1. 开封市食品药品检验所
  • 收稿日期:2015-10-29 修回日期:2015-12-01 出版日期:2015-12-25 发布日期:2015-12-25

Analysis on Adverse Drug Reaction/Event of 44 Cases of Invert Sugar Injection

谢晓燕   

  1. Kaifeng Institute of food and drug control
  • Received:2015-10-29 Revised:2015-12-01 Online:2015-12-25 Published:2015-12-25

摘要: 目的:分析转化糖注射剂不良反应的临床特点,以期为临床安全合理用药及临床护理提供参考。方法:检索2007~2014年开封市44例转化糖注射剂不良反应报告,采用回顾性研究的方法,对其性别、年龄、药品品种、用药原因、发生年份、用药情况、不良反应的类型以及累计器官等进行统计和分析。结果:44份报告中,男性患者26例(59.09%),女性患者18例(40.91%)。不良反应累及多系统-器官,临床表现复杂多样,主要以心外血管系统损害居多(31.58%),其次为全身性损害等,说明书中多无相关风险提示,为新的不良反应。结论:重视转化糖注射剂对静脉血管的损害,密切防范不良反应的发生,完善说明书,确保临床用药安全。

Abstract: Objective: To analyze the adverse reactions of invert sugar injection in clinical characteristics and provide rational and safety drug using and nursing in clinic as references. Methods: In national monitoring system of adverse drug reactions, we searched 44 reports about adverse reactions of invert sugar injection in our city from 2007 to 2014.We used retrospective analysis to statistically analyze adverse reactions of invert sugar injection in gender, age, drug variety and the reasons, the years, what happened when the drug being used, the types and which organs were related to the adverse reactions. Results: There are 26 male patients (59.09%) and 18 female patients (40.91%) of the 44 reports. Adverse reactions involved in multiple organs, systems, complicated and varied clinical manifestations, which mainly damaged the vascular system (31.58%) and then caused systemic damage. But there is no any warning in the instructions. So these adverse reactions may act as new ones. Conclusion: It is important to pay attention to the damages of invert sugar injection in vein, prevent serious adverse reactions from happening, complete instructions and ensure safety drug using in clinic.