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呼吸兴奋剂协同无创正压通气治疗 COPD并肺性脑病的疗效分析

李晓川   

  1. 辽阳市中心医院呼吸三科
  • 收稿日期:2016-08-26 修回日期:2016-08-26 出版日期:2016-12-25 发布日期:2016-12-26

Respiratory Stimulant Synergy Noninvasive Positive Pressure Ventilation Curative Effect Analysis for the Treatment of COPD and Pulmonary Encephalopathy

  1. Department of respiratory,Central Hospital of Liaoyang of Liaoning Province,Liaoyang,111000
  • Received:2016-08-26 Revised:2016-08-26 Online:2016-12-25 Published:2016-12-26

摘要: 目的:探讨呼吸兴奋剂协同无创正压通气治疗慢性阻塞性肺疾病(COPD)并肺性脑病的疗效。方法:收集2014年1月至2016年1月我院收治的COPD并肺性脑病患者,共计84例。以随机数字表将84例患者均分为对照组与研究组各42例。对照组行常规治疗及无创正压通气治疗,研究组在此基础上应用尼可刹米(呼吸兴奋剂)治疗。结果:治疗前血气分析结果比较中,两组间差异无统计学意义(P>0.05);治疗后血气分析结果比较中,研究组PaO2、SaO2、pH高于对照组(P<0.05),PaCO2低于对照组(P<0.05)。研究组无创通气治疗时间(6.2±2.3)d,低于对照组(8.3±2.3)d(P<0.05)。结论:呼吸兴奋剂协同无创正压通气治疗COPD并肺性脑病疗效可靠,适于临床推广。

Abstract: Objective: To study the respiratory stimulant synergy noninvasive positive pressure ventilation in patients with chronic obstructive pulmonary disease (COPD) and the curative effect of pulmonary encephalopathy. Methods: The clinical data from January 2014 to January 2014, our hospital patients with COPD and pulmonary encephalopathy, a total of 84 cases. In a random number table 84 patients were divided into control group and the team all the 42 cases. Control group routine treatment and noninvasive positive pressure ventilation therapy, the team on the basis of the application of nikethamide (respiratory stimulant) treatment. Results: The blood gas analysis results compared before treatment, there was no statistically significant difference between the two groups (P>0.05); After treatment the blood gas analysis results comparison, the team PaO2, SaO2, pH are higher than the control group (P<0.05), PaCO2 is lower than the control group (P<0.05). Team of noninvasive ventilation treatment time (6.2±2.3) d, lower than the control group (8.3±2.3), d (P<0.05). Conclusion: Respiratory stimulant synergy noninvasive positive pressure ventilation in the treatment of COPD and pulmonary encephalopathy therapeutic effect is reliable, suitable for clinical promotion.