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• 药品评价-临床研究 • 上一篇    下一篇

246例注射用丁二磺酸腺苷蛋氨酸临床使用情况分析

陈云艳,文娱,李晓晖   

  1. 厦门市中医院,厦门市中医院,厦门市中医院
  • 收稿日期:2019-01-11 修回日期:2019-02-20 出版日期:2019-02-25 发布日期:2019-02-25

Analysis of Clinical Application of Ademetionine 1,4-Butanedisulfonate for Injection in 246 Patients

Chen Yunyan, and   

  1. Xiamen Hospital of TCM,Wen Yu,
  • Received:2019-01-11 Revised:2019-02-20 Online:2019-02-25 Published:2019-02-25

摘要: 目的:调查分析注射用丁二磺酸腺苷蛋氨酸的临床使用情况,为临床合理用药提供参考。方法:利用医院信息系统回顾性分析我院2017年1~3月注射用丁二磺酸腺苷蛋氨酸的使用情况,对用药原因、适应证、用法用量、联合用药等进行统计分析。结果:246例使用注射用丁二磺酸腺苷蛋氨酸的患者中,最常见的用药原因为肝胆系统合并肝功能异常(61.79%);患者主要分布在肝病中心(51.79%);日剂量基本为1 g(94.72%)。我院注射用丁二磺酸腺苷蛋氨酸多为联合使用(58.54%),以联合注射用还原型谷胱甘肽居多,单独使用的情况较少(11.79%)。未见与药物相关的不良反应。结论:我院注射用丁二磺酸腺苷蛋氨酸使用情况基本合理。

Abstract: To investigate and analyze the application of Ademetionine 1,4-Butanedisulfonate for injection in clinic,and provide the reference for rational drug use. Methods: The clinical data of the in-patients who were treated by Ademetionine 1,4-Butanedisulfonate for injection in our hospital from January to March 2017 in respective of medical reasons, usage and dosage ,combination treatment. Results:The majority disease of 246 patients using Ademetionine 1,4-Butanedisulfonate for injection was hepatobiliary system disease accompanied with liver function, accounting for 61.79%. The largest number of patients was in the Liver Research Center(51.79%). About 94.27% of the patients were given the daily dose of 1g.In our hospital, the majority of Ademetionine 1,4-Butanedisulfonate for injection was used in combination (58.54%), which was used in combination with glutathione,and the proportion of Ademetionine used alone was less (11.79%). No drug-related adverse reactions were observed. Conclusion:The application of Ademetionine 1,4-Butanedisulfonate in our hospital was basically rational.