• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

中国药物评价 ›› 2019, Vol. 36 ›› Issue (6): 420-422.

• 评价技术与方法 • 上一篇    下一篇

RP-HPLC法测定滑膜炎颗粒和滑膜炎片中特女贞苷的含量

张静娇1,康凯2,鄢长余2,周凌2, 胡景莲2,赵月然2   

  1. 1. 大连市药品检验所
    2. 大连市检验检测认证技术服务中心
  • 收稿日期:2020-01-19 出版日期:2019-12-28 发布日期:2020-01-21

Determination of Specnuezhenide in Synovitis Granules and Synovitis Tablets by RP-HPLC

  • Received:2020-01-19 Online:2019-12-28 Published:2020-01-21

摘要: 目的:建立高效液相色谱法测定滑膜炎颗粒和滑膜炎片中特女贞苷含量的方法。方法:选用Thermo Acclaim 120 C18色谱柱;检测波长为224 nm;流速:1.0 mL·min-1;柱温:30 ℃。结果:特女贞苷的质量浓度与峰面积分别在7.42~37.10 μg·mL-1范围呈良好的线性关系;回归方程分别为Y=12 517 035X+466.50(r=1.000 0)。结论:该方法准确,简便,灵敏,可作为滑膜炎颗粒和滑膜炎片中控制女贞子质量的方法。

Abstract: Objective:Established a RP-HPLC method of the contentdetermination of Specnuezhenidein Synovitis Granules and Synovitis Tablets. Methods:Thermo Acclaim 120 C18column was used. The detection wavelength was set at 224 nm .The flow rate was 1.0 mL·min-1. The column temperature was maintained at 30 ℃. Results:Specnuezhenide was linear in the range from 7.42 to 37.10 μg·mL-1and the regression equation was Y=12 517 035X+466.50 (r=1.000 0). Conclusion:The method is accurate, simple and feasible, and can be used as an ideal method for the quality control of Ligustri Lucidi Fructusin Synovitis Granules and Synovitis Tablets.

中图分类号: