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中国药物评价 ›› 2020, Vol. 37 ›› Issue (4): 257-261.

• 药物研究 • 上一篇    下一篇

中药蛴螬的质量标准及研究进展

赵艳1, 李正刚1, 王路宏1, 孙艳涛2, 赵磊1*, 昝珂3*   

  1. 1. 四平市食品药品检验所, 吉林 四平 136000;
    2. 吉林师范大学化学学院, 吉林 四平 136000; 3. 中国食品药品检定研究院, 北京 100050
  • 收稿日期:2020-03-31 修回日期:2020-05-27 出版日期:2020-08-28 发布日期:2020-09-21
  • 基金资助:
    吉林省地方药材标准化2017项目

Quality Standard and Research Progress of Traditional Chinese Medicine Holotrichia diomphalia Larvae

  1. 1. Siping Institute for food and Drug Control, Jilin Siping 136000, China;
    2. Jilin Normal University College of Chemistry, Jilin siping 136000, China;
    3. National Institutes for Food and Drug Control, Beijing 100050, China
  • Received:2020-03-31 Revised:2020-05-27 Online:2020-08-28 Published:2020-09-21
  • Contact: zhao zhaolei E-mail:zhaolei0433@sina.com

摘要: 对中药材蛴螬的检测标准及其药物应用进行综述。蛴螬在地域分布上存在的种属差异,导致不同省级标准在药物基源上不同。对蛴螬炮制方法和检测方法进行分类,明确蛴螬含有核苷、氨基酸、肽类、酚性成分脂肪酸、烷烃类、生物碱、甾体化合物、微量元素及维生素类;活性具有抗菌、抗肿瘤,治疗眼疾、保肝、抗菌等作用。通过研究发现蛴螬在药物开发方面具有良好的发展前景。

关键词: font-size:medium, ">蛴螬; 质量标准; 化学研究; 药理学

Abstract: The detection standard of Holotrichia diomphalia larvae in traditional Chinese medicine and its application in medicine were reviewed. The difference of provincial standard in drug base, the classification of processing method and the difference of detection method. Chemical Studies showed that Holotrichia diomphalia larvae contained nucleosides, amino acids, peptides, phenolic components, fatty acids, alkanes, alkaloids, steroids, micronutrient and vitamins. Pharmacology has antibacterial, anti-tumor, treatment of eye disease and other effects. It was found that the holotrichia diomphalia larvae had a good prospect in drug development.
    

Key words: font-size:medium, ">Holotrichia diomphalia larvae; Quality standard; Chemical studies; Pharmacology

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