• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

中国药物评价 ›› 2021, Vol. 38 ›› Issue (4): 343-346.

• 药品评价 • 上一篇    下一篇

肿瘤患者预防性止吐药物使用规范性分析

李雪芹, 曲爱美, 郭其*   

  1. 滨州医学院烟台附属医院,山东 烟台 264100
  • 收稿日期:2021-05-24 修回日期:2021-04-02 出版日期:2021-08-28 发布日期:2021-09-14

Analysis of Normative Use of Preventive Anti-emetic Drugs in Cancer Patients

 LI Xue-qin, QU Ai-mei, GUO Qi*   

  1. Yantai Affiliated Hospital of Binzhou Medical University, Yantai 264100, China
  • Received:2021-05-24 Revised:2021-04-02 Online:2021-08-28 Published:2021-09-14

摘要: 目的: 通过对肿瘤患者预防性止吐药物使用分析,为临床合理用药提供参考。方法: 利用医院HIS系统,回顾性调查医院肿瘤科2020年1~12月首次接受抗肿瘤治疗的患者医嘱病例875例,对治疗过程中预防性止吐药物使用情况进行评价分析。结果: 在调查的875例中,599例符合纳入排除标准,334例(55.76%)存在不合理用药;不合理用药包括联合用药不规范(14.07%)、用药疗程不规范(51.80%)、止吐方案级别选择不规范(34.13%);规范预防组恶心呕吐的控制率明显优于不规范用药组(64.91% VS 48.80%,P<0.05)。结论: 我院预防性止吐方案的选择存在不足,临床医师应根据抗肿瘤方案规范性选择止吐方案,降低恶心呕吐的发生,提高患者治疗依从性和生活质量,促进临床合理用药。
   

关键词: font-size:13.3333px, ">预防性止吐药物;化疗引起恶心呕吐;规范性;肿瘤患者

Abstract: Objective: By analyzing the preventive anti-emetic drugs in Cancer Patients to provide reference for clinical rational medication. Methods: Using the hospital HIS system to retrospectively investigate 875 patients who received the first anti-tumor treatment in the department of oncology of the hospital from January to December 2020 and analyze the use of preventive anti-emetic drugs during the treatment. Results: Among the 875 cases investigated,599 cases met the inclusion and exclusion criteria,and 334 cases(55.76%)had irregular drug use.Non-standard medication includes non-standard combination medication(14.07%), non-standard medication course(51.80%) and non-standard anti-emetic program level selection(34.13%). The control rate of nausea and vomiting in the standard prevention group was significantly better than that in the non-standard medication group(64.91% vs 48.80%,P<0.05). Conclusion: The choice of preventive anti-emetic plan in our hospital is insufficient.Clinicists should choose the standard plan to stop vomiting according to the anti-tumor regimens to reduce the happening of nausea and vomiting,improve the treatment compliance and the quality of the life of patients, and promote clinical rational use of drugs.

Key words: font-size:13.3333px, ">Preventive anti-emetic drugs; Chemotherapy-induced nausea and vomiting; Normalization; Cancer patients

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