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中国药物评价 ›› 2021, Vol. 38 ›› Issue (6): 528-530.

• 药品评价 • 上一篇    下一篇

莫沙必利联合复方消化酶治疗功能性消化不良的临床观察

 禹孝伟   

  1. 河南大峪沟煤业集团有限责任公司职工医院,河南 巩义 451271
  • 收稿日期:2021-08-31 修回日期:2021-10-25 出版日期:2021-12-28 发布日期:2021-12-28

Clinical Observation of Mosapride Combined with Compound Digestive Enzyme in Treatment of Functional Dyspepsia

  1. Department of internal medicine, staff hospital of Henan Dayugou Coal Industry Group Co., Ltd., Henan Gongyi 451271,China
  • Received:2021-08-31 Revised:2021-10-25 Online:2021-12-28 Published:2021-12-28

摘要: 目的:研究莫沙必利与复方消化酶联合治疗功能性消化不良的临床疗效。方法:选取我院内科2019年1月至2020年12月就诊的功能性消化不良患者120例,按数字随机表法分为治疗组和对照组,每组各60例;对照组口服莫沙必利治疗,治疗组服用莫沙必利联合复方消化酶治疗,比较两组的临床疗效、生活质量、不良反应发生率和复发率。结果:经治疗,治疗组的总有效率为91.67%,高于对照组的81.67%,P<0.05;治疗组的FDDQL评分高于对照组,P<0.05。治疗组的不良反应发生率为1.67%,低于对照组的8.33%,P>0.05;治疗组的复发率为3.33%,低于对照组的11.67%,P>0.05。结论:莫沙必利与复方消化酶协同治疗功能性消化不良疗效确切,有效提高生活质量,减轻不良反应发生率,具有较高的安全性,可为临床用药提供参考。
     

关键词: font-size:medium, ">功能性消化不良;莫沙必利;复方消化酶;疗效;生活质量

Abstract: Objective: The clinical effect of Mosapride and compound digestive enzyme in treatment of functional dyspepsia was studied.Methods: 120 functional dyspepsia patients treated in department of internal medicine in our hospital from January 2019 to December 2020 were divided into treatment group and control group stochastically, with 60 cases in each group; The control group were treated with Mosapride, and treatment group were treated with Mosapride combined with compound digestive enzyme. The clinical effect, quality of life, adverse reaction rate and recurrence rate between the two groups were compared.Results: After treatment, the total effective rate of treatment group was 91.67%, higher than 81.67% of control group, P<0.05. The FDDQL score of treatment group was higher than control group, P<0.05. The incidence of adverse reactions in treatment group was 1.67%, lower than 8.33% of control group, P>0.05. The recurrence rate in treatment group was 3.33%, lower than 11.67% of control group, P>0.05. Conclusion: The treatment of mosabil and compound digestive enzyme for patients with functional dyspepsia is exactly effective, improve life quality of patients, reduce the incidence of adverse reactions in patients, has a high safety, and can provide reference for clinical medication.
     

Key words: Functional dyspepsia, Mosapride, Compound digestive enzyme, Curative effect, Quality of life

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