关键词: font-size:medium, ">复方银杏通脉口服液；HPLC；指纹图谱；含量测定

Abstract: Objective：Estalish the fingerprint and Three active Content Determination of Compound Yinxing Tongmai Oral Liquid. Methods：Waters xterra C18 column(250 mm×4.6 mm， 5 μm) UV detector was used； the moile phase was acetonitrile(A)-0.1% phosphoric acid water(B)， gradient elution， detection wavelength 224 nm， and the injection volume was 20 μL. Results： The fingerprints of 10 atches of Compound Yinxingtongmai Oral Liquid identified 27 common peaks and identified 4 components. The similarity of 10 atches of samples and the control map were all greater than 0.985. Stilene glycosides， secretinosidesand salvianolic acid， linear relationshipwere shown at 0.41 μg-2.07 μg(R2=1)； 0.49 μg-2.43 μg(R2=1)； 0.47 μg-2.35 μg(R2=0.999)， respectively. The average recovery rates of stilbeneside， Privet Glycoside， and Danphenolic Acid B were 96.76%， 94.52%， and 111.66%(n=9)， and the RSDs were 2.97%， 2.27%， and 3.29%， respectively. Conclusion： The method estalished in this study is stale and reliale， and can provide a asis for the susequent quality improvement of Compound Yinxingtongmai Oral Liquid.

Key words: font-size:medium, ">Compound yinxingtongmai oral liquid； High performance liquid chromatography(HPLC)； Fingerprint；Content determination