• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

中国药物评价 ›› 2023, Vol. 40 ›› Issue (2): 107-114.

• 专栏—中医药疗效评价 • 上一篇    下一篇

基于数据挖掘的中医药防治新型冠状病毒感染老年人群用药规律分析

马伊昕1, 孙鑫1, 吴晓丹1, 孟闫燕2, 费宇彤1,3,4, 荣红国1,3,4,5*   

  1. 1.北京中医药大学中医学院, 北京100700;
    2.北京中医药大学北京中医药研究院, 北京 100029;
    3.北京中医药大学国际循证中医药研究院, 北京100029;
    4.北京中医药大学循证医学中心, 北京 100029;
    5.北京中医药大学国家中医药发展与战略研究院, 北京 100029
  • 收稿日期:2023-02-22 修回日期:2023-03-06 出版日期:2023-04-28 发布日期:2023-04-28
  • 基金资助:
    北京中医药大学2022年度基本科研业务费(2022-JYB-PY-013);北京中医药大学2021年度教育科学研究课题(XJY21013)

Analysis of Medication Patterns in Traditional Chinese Medicine for the Prevention and Treatment of COVID-19 in the Elderly Based on Data Mining

  1. 1.School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    2.Beijing Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    3.Institute for Excellence in Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    4.Center for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
    5.National Institute of Chinese Medicine Development and Strategy, Beijing University of Chinese Medicine, Beijing 100029, China
  • Received:2023-02-22 Revised:2023-03-06 Online:2023-04-28 Published:2023-04-28

摘要: 目的:整理分析国家及各省市最新发布的新型冠状病毒感染(简称新冠病毒感染)中医药防治方案,探究老年人群中医药用药规律。方法:收集整理2023年1月10日(含)之前国家及各省、自治区、直辖市,及省会城市和地级市卫生健康委员会(卫健委)、中医药管理局(中管局)最新发布的新冠病毒感染中医药防治方案。利用古今医案云平台(V2. 3. 5)分析防治老年人群新冠病毒感染中医药核心药物组成、四气五味归经、组方规律等。结果:本研究纳入30份新冠病毒感染中医药防治方案。针对老年群体推荐防治中药处方共79首(预防处方46首、治疗处方33首),未见恢复期处方。老年群体新冠病毒感染主要治法有益气温阳、肺肠同治、清热化痰等。预防处方与治疗处方用药对比显示,预防处方药物主要有防风、黄芪、白术、金银花等,药性以微温性为主,药味以甘味为主,归经以归肺、脾经多见;治疗处方药物主要有金银花、甘草、芦根、苦杏仁等,药性以寒性为主,药味以甘、苦、辛为主,归经以归肺、胃、脾、心经多见。基础疾病与中药关联分析提示不同基础疾病常用药物。结论:老年人群预防以祛风益气固表、补气健脾等为原则,治疗用药以宣肺散邪、清热祛湿为主。老年患者治疗应根据临床症状,辨别不同证候确定治法,遵循中医药“辨证论治”“因人制宜”“扶正祛邪”基本原则。伴有基础疾病者可随证加减。建议增加恢复阶段推荐处方,切实提高老年人健康水平。

关键词: font-size:medium, ">新型冠状病毒感染;老年人;中医药;数据挖掘;用药规律

Abstract: Objective:To systematically analyze traditional Chinese medicine (TCM) prescription pattern of COVID-19 and investigate the patterns of TCM used in the elderly. Methods:To organize the latest TCM prevention and treatment protocols for COVID-19 by the National, Provincial and Municipal Health Commissions and administrations before January 10, 2023 (inclusive), and develop a data extraction table. The ancient and modern medical case cloud platform (V2. 3. 5) was used to analyze the composition of Chinese medicine drugs used in the elderly. Results: Thirty protocols for were included. A total of 79 herbal prescriptions were recommended for the elderly, and no prescription for recovery. The main treatment methods were beneficial to qi and yang, lung and intestine together, and clearing heat and phlegm. The comparison between the prescriptions for prevention and the prescriptions for treatment showed that the drugs mainly included Fangfeng, Huangqi and Atractylodes, which were slightly warm in nature and sweet in taste, and were attributed to the lung and spleen meridians. The drugs prescribed for treatment mainly included Jinyinhua, licorice, rhizome and bitter almond, which were mainly cold in nature and sweet, bitter, and pungent in taste, and were mostly attributed to the lung, stomach, spleen and heart meridians. The correlation analysis between underlying diseases and traditional Chinese medicine suggested common symptoms and drugs.Conclusion:The principle of prevention is to dispel wind, benefit qi and consolidate the surface, and tonify qi and strengthen the spleen, while the treatment is mostly based on promoting the lung and dispersing evil, clearing heat and dispelling dampness. The treatment should be based on clinical symptoms, identify different types of symptoms, and follow the basic principles and ideas of Chinese medicine treating based on pattern differentiation, adapting to the individual, and supporting the righteous and eliminating the evil. Elderly patients with underlying diseases can be treated with additional prescriptions according to the evidence. It is recommended to increase recovery prescription to effectively improve the health of the elderly.

Key words: font-size:medium, ">COVID-19; Elderly;Traditional Chinese medicine;Data mining;Medication patterns

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