关键词: font-size:medium, ">银杏注射制剂；药品不良反应；信号检测；数据分析

Abstract: To compare the occurrence of ADR of ginkgo injection preparations(Shuxuening injection， ginkgo Damo injection， ginkgo extract injection， ginkgolide injection， xingxiong sodium chloride injection and ginkgolide glucosamine injection) in Henan Province ADR monitoring system. so as to provide reference basis for clinical rational drug use and drug risk assessment. Methods： The adverse drug reaction information of suspected ginkgo injection collected by the spontaneous adverse drug reaction reporting system of Henan Province from 2014 to 2021 was compared and analyzed. Results & Conclusion： Reports of adverse reactions of ginkgo injection were mainly from medical institutions. The gender distribution of the population is generally uniform. The patients were more than 60 years old. The main ADR were general adverse reactions， including pruritus， rash， nausea， flushing， fever， etc. The new ADR include dyspnea， palpitation， phlebitis， insomnia and so on. For new ADR. It is recommended that drug marketing authorization holders strengthen monitoring and actively carry out signal monitoring and risk assessment.

    

Key words: font-size:medium, ">Ginkgo biloba injection preparation； Adverse drug reactions； Signal detection； Data analysis