Abstract: Objective： To analyze the effect of small doses of ropivacaine combined spinal-epidural anesthesia (CSEA) on hemodynamics and anesthesia quality in pregnant women with cesarean section. Methods： 130 pregnant women with selective cesarean section from September 2014 to February 2017 were selected， and they were randomly divided into experimental group and control group， 65 cases in each group. Two groups were given spinal anesthesia， experimental group was given 0.75% ropivacaine hydrochloride 1 mL and water for injection 2 mL， while control group was given 0.75% ropivacaine hydrochloride 1 mL and water for injection 1 mL. The anesthesia plane fixed time， anesthesia time， muscle relaxant satisfaction， incidence of adverse reactions were compared between the two groups. Results： Before anesthesia， after anesthesia for 15min and after surgery， there was no statistical difference in the HR， MAP， SPO2 between the two groups (P>0.05)； After delivery， the HR of control group increased， while MAP and SPO2 decreased (P<0.05). There was no statistical difference in the anesthesia plane， anesthesia plane holding time and muscle relaxant satisfaction between the two groups (P>0.05). The anesthesia plane extinction time of experimental group was shorter than that of control group (P<0.05). After delivery for 1min， there was no statistical difference in the Apgar score between the two groups (P>0.05). The incidence of adverse reactions in experimental group (7.69%) was lower than control group (30.77%) (P<0.05). Conclusion： Small doses of ropivacaine CSEA in pregnant women with cesarean section can stabilize hemodynamic indexes， decrease the incidence of adverse reactions， increase anesthesia quality.