• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

• 药品评价-临床研究 • 上一篇    下一篇

罗哌卡因腰-硬联合麻醉对剖宫产孕妇 血流动力学及麻醉质量的影响

孟婧雅   

  1. 巩义市阳光医院
  • 收稿日期:2017-10-27 修回日期:2017-11-13 出版日期:2017-12-25 发布日期:2017-12-25

Effect of Ropivacaine Combined Spinal-epidural Anesthesia on Hemodynamics and Anesthesia Quality in Pregnant Women with Cesarean Section

Meng Jingya   

  1. Gongyi sunshine hospital
  • Received:2017-10-27 Revised:2017-11-13 Online:2017-12-25 Published:2017-12-25

摘要: 目的:分析小剂量罗哌卡因联合麻醉应用于剖宫产孕妇的血流动力学改变和麻醉质量情况。结果:本研究选取2014年9月至2017年2月期间我院收治的择期剖宫产孕妇130例作为研究对象,并随机划分为试验组和对照组,各65例,两组患者均予以腰麻方式,试验组采取0.75%盐酸罗哌卡因1 mL+注射用水2 mL,对照组采取0.75%盐酸罗哌卡因2 mL+注射用水1 mL,对比两组产妇的麻醉平面固定所需时长、麻醉时长、肌肉松弛满意程度及不良反应发生比例。结果:麻醉前、麻醉15分值及手术完毕,两组产妇的心率(HR)、平均动脉压(MAP)、血氧饱和度(SPO2)指标比较差异无统计学意义(P>0.05)。胎儿完成分娩后对照组HR显著增快,MAP与SPO2显著下降,且差异具有统计学意义(P<0.05),两组产妇在麻醉平面、麻醉平面维持时间及肌肉松弛满意程度方面比较差异无统计学意义(P>0.05)。试验组产妇麻醉平面消退时间明显短于对照组(P<0.05),两组新生儿分娩完毕后1分钟Apgar分数对比差异无统计学意义(P>0.05),试验组和对照组的不良反应发生率分别为7.69%、30.77%,试验组的不良反应发生率显著低于对照组(P<0.05)。结论:小剂量罗哌卡因联合麻醉应用于剖宫产孕妇具有血流动力学指标稳定、不良反应发生率低的优势,能够有效提高麻醉质量。

Abstract: Objective: To analyze the effect of small doses of ropivacaine combined spinal-epidural anesthesia (CSEA) on hemodynamics and anesthesia quality in pregnant women with cesarean section. Methods: 130 pregnant women with selective cesarean section from September 2014 to February 2017 were selected, and they were randomly divided into experimental group and control group, 65 cases in each group. Two groups were given spinal anesthesia, experimental group was given 0.75% ropivacaine hydrochloride 1 mL and water for injection 2 mL, while control group was given 0.75% ropivacaine hydrochloride 1 mL and water for injection 1 mL. The anesthesia plane fixed time, anesthesia time, muscle relaxant satisfaction, incidence of adverse reactions were compared between the two groups. Results: Before anesthesia, after anesthesia for 15min and after surgery, there was no statistical difference in the HR, MAP, SPO2 between the two groups (P>0.05); After delivery, the HR of control group increased, while MAP and SPO2 decreased (P<0.05). There was no statistical difference in the anesthesia plane, anesthesia plane holding time and muscle relaxant satisfaction between the two groups (P>0.05). The anesthesia plane extinction time of experimental group was shorter than that of control group (P<0.05). After delivery for 1min, there was no statistical difference in the Apgar score between the two groups (P>0.05). The incidence of adverse reactions in experimental group (7.69%) was lower than control group (30.77%) (P<0.05). Conclusion: Small doses of ropivacaine CSEA in pregnant women with cesarean section can stabilize hemodynamic indexes, decrease the incidence of adverse reactions, increase anesthesia quality.