关键词: font-size:medium, ">清瘟解毒片；葛根素；牛蒡苷；高效液相色谱法

Abstract: Objective： The contents of puerarin， paeoniflorin， Liquiritin， 5-O-Methylvisamminoside， baicalin， actiin，hillyrin and arctigenin in Qingwenjiedu Tablets were simultaneously determined by HPLC. Methods： The chromatographic column type is Agilent TC-C18 (4.6 mm×250 mm， 5 μm)， and the mobile phase composition is acetonitrile： 0.2% acetic acid (gradient elution).the flow rate was 1.0 mL·min-1， the temperature was 30 ℃ and the injection was 10 μL. Results： Puerarin， Paeoniflorin，Liquiritin， 5-O-Methylvisamminoside， Baicalin， actiin， phillyrin， arctigenin， 0.040 4-4.04， 0.019 4-0.778， 0.000 243 6-0.024 36， 0.020 9-0.836， 0.021 6-0.862， 0.033-1.32， 0.016 1-0.644， 0.025 8-1.032 mg·mL-1， it′s linear in scope. The contents of puerarin， paeoniflorin， Liquiritin， 5-O-Methylvisamminoside，baicalin，actiin，phillyrin and arctigenin were 6.43， 0.78， 0.232 6， 0.168， 8.09， 5.87， 0.25， 0.67 mg·g-1， respectively. Conclusion： This method is specific， accurate， reliable， simple and convenient， which provides a theoretical basis for the quality control of Qingwenjiedu Tablets.

Key words: font-size:medium, ">Qingwenjiedu Tablets； Puerarin； Arctiin； High performance liquid chromatography(HPLC)