• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

中国药物评价 ›› 2021, Vol. 38 ›› Issue (2): 122-129.

• 药品评价 • 上一篇    下一篇

儿童抗菌药物使用情况分析

贾俊琴, 宋沧桑, 孙艳芳, 秦芳   

  1. 昆明市第一人民医院, 云南 昆明 650034
  • 收稿日期:2020-10-13 修回日期:2021-03-16 出版日期:2021-04-28 发布日期:2021-04-28

Analysis of Antimicrobial Drug Use in Children

JIA Jun-qin, SONG Cang-sang, SUN Yan-fang, QIN Fang   

  1. Kunming Municipal First People′s Hospital, Yunnan Kunming 650034, China
  • Received:2020-10-13 Revised:2021-03-16 Online:2021-04-28 Published:2021-04-28

摘要: 目的:了解某院2019年儿科住院患者抗菌药物使用情况,为促进儿童合理用药提供参考。方法:回顾性方法调查某院2019年儿科住院患者抗菌药物使用数据。结果: 某院2019年共1 720例患儿接受抗菌药给药治疗。抗菌药物使用率和使用强度分别为77.67%和31.92;疾病情况:NICU区先天性肺炎占首位(50.5%),普儿区排在第一、二位的是肺炎支原体性肺炎,支原体感染;使用抗菌药物静脉给药为主要途径(97%);NICU区使用频率最高的是注射用哌拉西林钠舒巴坦钠,普儿区为注射用头孢甲肟;NICU区抗菌药物联合用药率为7.01%,普儿区为36.92%;以CDUI(儿童药物利用指数)评价儿童用药剂量合理性提示不同年龄段均存在抗菌药物用药剂量不合理的问题。结论: 儿科住院患者抗菌药物使用率和使用强度偏高,静脉注射用药比例高;使用抗菌药物基本合理,但经验性治疗和联合用药时建议尽量明确用药指征;通过计算抗菌药物使用的CDUI(儿童药物利用指数),部分药品的使用欠合理,仍然需要加强监督管理和使用指导。
 

关键词: font-size:medium, ">儿童药物利用指数;抗菌药物;限定日剂量;合理用药

Abstract: Objective: To understand the use of antimicrobial agents in pediatric inpatients in hospital in 2019, so as to provide reference for promoting rational drug use in children. Methods: Data on antimicrobial use of pediatric inpatients in hospital in 2019 were investigated retrospectively.Results: Hospital in 2019, a total of 1 720 cases accepted antibiotic medication. Antimicrobial usage and intensity of use were 77.67% and 31.92 respectively. Disease status: congenital pneumonia was the most common (50.5%) in the NICU region, with mycoplasma pneumoniae (mycoplasma infection) ranking first or second in the general region. Intravenous antibiotic administration was the main route (97%). In the NICU region, the highest frequency of use was piperacillin sodium sulbactam sodium for injection and cefmenoxime for injection. The combined use rate of antibiotics in NICU region was 7.01% and that in puer region was 36.92%. With CDUI rationality evaluation of children dosage hint at different ages are antibacterial drug dosage unreasonable problems.Conclusion: The utilization rate and intensity of antibacterial drugs in pe-diatric inpatients were higher, and the proportion of intravenous drugs was higher. The use of antimicrobial agents is basically reasonable, but it is recommen-ded to clarify the indications for the use of antimicrobial agents as far as pos-sible in the case of empirical treatment and combined use. By calculating the C-DUI of antimicrobial drug use, it can be found that the use of some drugs is not reasonable, and the supervision, management and guidance on the use still need to be strengthened.

Key words: Key words:drug use index for children, antimicrobial agents, Medication frequency, Limited daily dose

中图分类号: